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The data regarding the association between COMT Val
2021-05-07
The data regarding the association between COMT Val158/108Met and cognitive function are divergent [10,11,12,22,24,25,26,27,28]. Better performance on the ROCF immediate and delayed recall test among veterans with PTSD who were Met carriers, compared to Val/Val homozygotes, agrees with findings show
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In patients with CTEPH ET levels are
2021-05-07
In patients with CTEPH, ET-1 levels are raised and have been shown to fall after PEA surgery [24]. After an acute pulmonary embolism there is obstruction of the pulmonary sb202190 by acute thrombus and elevated levels of ET-1 [28], [30]. Elevated levels of ET-1 have also been observed in air embolu
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A putative SHBG receptor SHBG R has
2021-05-07
A putative SHBG Lomerizine HCl (SHBG-R) has been postulated for about thirty years [66], [69], [70]. The characterization of this receptor has been researched by several groups. There are different ideas on how this receptor works. On the one hand Fortunati et al. provide evidence that SHBG is alrea
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Within the availability of large number
2021-05-07
Within the availability of large number of experimental data, it is easy to develop the relation between the mechanical strength and corrosive resistance of the RHA added cement concrete. The developed correlation is given in the following Eq. (4.8). This equation can be used to predict any of the
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br Introduction Hematopoietic stem cells
2021-05-07
Introduction Hematopoietic stem jzl and leukemic stem cells (HSCs and LSCs, respectively) both have a capacity of self-renewal. Whereas HSCs give rise to all blood lineages during lifetime hematopoiesis, LSCs are responsible for the initiation and propagation of leukemia, as well as drug resista
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Treatment with AAV EP also improved aspects of adverse
2021-05-07
Treatment with AAV9-EP4 also improved aspects of adverse cardiac remodeling. The increased collagen deposition noted in the peri infarct and remote zone after MI was substantially attenuated by use of AAV9-EP4 and there were significant reductions in the number of macrophages and T Bisindolylmaleimi
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Related with the studies by Zizza et
2021-05-07
Related with the studies by Zizza et al. described above [66], work by Ward et al. [68] suggested that the C2 domain of cPLA2α, which binds to zwitterionic membranes with high affinity in a Ca2+-dependent manner, has a high membrane remodeling activity, producing dramatic changes in membrane curvatu
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To our knowledge this is the first report of an
2021-05-07
To our knowledge, this is the first report of an oncocytoma expressing alpha-enolase or causing autoimmune retinopathy and optic neuropathy. Although generally considered benign, oncocytomas have rarely been associated with paraneoplastic syndromes, including tumor-induced hypertension, erythrocytos
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The present study showed evidence that the
2021-05-07
The present study showed evidence that the AT1 and the ETA receptors were not expressed near or on the plasma membrane as monomers, but also as possibly constitutive dimers and tetramers. For both receptors, the proportion of monomers, dimers and tetramers were unaffected by their respective agonist
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In conclusion we provide convincing evidence that the
2021-05-07
In conclusion, we provide convincing evidence that the PRRSV-induced SGs are indeed bona fide SGs. While we determined that mRNA is present in the PRRSV-induced SGs, we did not distinguish its origin. Future studies will need to determine whether the mRNA stored in PRRSV-induced SGs is of cellular o
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Z-IETD-FMK In plants SUMOylation has been shown to modulate
2021-05-07
In plants, SUMOylation has been shown to modulate plant hormone signaling (Lois et al., 2003, Miura et al., 2009, Conti et al., 2014), root stem cell maintenance (Xu et al., 2013), and responses to abiotic and biotic stress (Lois, 2010). Many of the plant biological processes regulated by SUMOylatio
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The BMP family comprises significant growth factors for the
2021-05-07
The BMP family comprises significant growth factors for the regeneration of bone and cartilage. Among these, BMP- has been known as an early marker during the proliferation of osteoblast cells, and one of the most potent stimulators of osteoblastic cells differentiation [40]. Studies with COX-2 knoc
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Consistent with our previous study Gao et
2021-05-07
Consistent with our previous study (Gao et al., 2018b; Wu et al., 2018), we found that TCB-2 disrupted both pup preference and home-cage maternal behavior. Based on the findings that 4-h pup CID 755673 (a technique presumably increases maternal motivation) failed to attenuate the TCB-2-induced mater
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DGK is highly expressed in skeletal muscle which is a
2021-05-07
DGKδ is highly expressed in skeletal muscle [7], which is a primary target of insulin for glucose disposal [14]. Notably, Chibalin et al. reported that DGKδ contributes to hyperglycemia-induced peripheral insulin resistance and that decreased protein levels of DGKδ in skeletal muscle attenuated glu
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br Introduction Alzheimer s disease AD is
2021-05-06
Introduction Alzheimer’s disease (AD) is the progressive version of mild cognitive impairment and usually met by the elderly population. It falls into the class of neurodegenerative disorders that attacks the PX 866 nerves cells, or neurons, resulting in loss of memory, impairment of thinking an
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