• SU 4312 Kim et al found that hydroxydopamine OHDA promoted t

  2024-11-28

  

  Kim et al. (2013) found that 6-hydroxydopamine (6-OHDA) promoted the atrophy of dopaminergic neurons associated with the activation of poly (ADP-ribose) polymerase (PARP), the translocation of apoptosis inductor factor (AIF) and the depletion of ATP. An increase in p-AMPK and pS6K (upstream kinase o

• br Acknowledgments This work was supported by a grant

  2024-11-28

  

  Acknowledgments This work was supported by a grant of the Romanian National Authority for Scientific Research, CNCS – UEFISCDI, project no. PN-II-ID-PCE-2011-3-0571, awarded to F.A.M. D.V.N. was co-financed from the European Social Fund through Sectorial Operational Program Human Resources Develo

• Curcumin is able to upregulate

  2024-11-28

  

  Curcumin is able to upregulate the protein level of NGF through cannabinoid receptor CB1, where the activation of Akt pathway probably plays an important part in the CB1-mediated signal transmission [9,10]. This finding suggested that the protection of curcumin in spinal motor neurons of SNI rats is

• br Functions essentially consisting in transport of substrat

  2024-11-28

  

  Functions essentially consisting in transport of substrates across plasma membranes Direct activation of neurotransmitter transporters elicits responses in neurons As previously mentioned (Section 2.1), nerve terminals handling classical transmitters possess transporters able to (re)capture se

• br Materials and methods br Results br Discussion

  2024-11-28

  

  Materials and methods Results Discussion In this study, we have demonstrated that the adiponectin system (genes and proteins) is present in the porcine endometrium (epithelial glandular cells, luminal epithelial rotenone and stromal cells) and myometrium (longitudinal and circular muscle la

• AdipoR and AdipoR have been reported

  2024-11-28

  

  AdipoR1 and AdipoR2 have been reported to be present in almost all type of tissues and low G-15 receptor levels have been observed in white adipose tissue (Inukai et al., 2005). These receptors have been observed to become deregulated with the onset of obesity, resulting in a reduced level of APN e

• We have previously shown that the antinociceptive effect of

  2024-11-28

  

  We have previously shown that the antinociceptive effect of tramadol, an analgesic that, like paracetamol is able to increase serotonin levels within CNS, is potentiated or antagonized respectively by a 5-HT1A/B nonspecific Pefloxacin Mesylate blockade or activation (Rojas-Corrales et al., 2000). M

• A correlation analysis was performed to

  2024-11-27

  

  A correlation analysis was performed to investigate a possible relationship between serum resistin levels and MG-ADL. We observed a significant relationship between serum resistin levels and MG-ADL scores in AChR-GMG-positive cases (r=0.285, p=0.032; Fig. 1C). There were also significant correlation

• br Conflict of interest br Acknowledgments This work was

  2024-11-27

  

  Conflict of interest Acknowledgments This work was supported by research grant [PR26/20326] from Santander Bank/UCM. The authors would like to thank Miguel Capo, Professor of Toxicology from the Universidad Complutense de Madrid, for his counseling during the preparation of the present work.

• br Results br Discussion Dopamine regulates behavioral respo

  2024-11-27

  

  Results Discussion Dopamine regulates behavioral responses to nicotine in Drosophila (Bainton et al., 2000), but neurochemical measurements of dopamine after nicotine stimulation had not been made. Here, we demonstrate for the first time that the stimulation of nAChRs causes dopamine release i

• Our analysis has devoted limited

  2024-11-27

  

  Our analysis has devoted limited attention to the standard corporate tax scheme with deductibility for interest payments that is in place in most countries. A conventional corporate tax scheme offers partial deduction of capital costs, and can be interpreted as a change in the degree of capital cost

• dopamine beta hydroxylase It has been reported that leukotri

  2024-11-27

  

  It has been reported that leukotrienes and their receptors, e.g. the cysteinyl leukotriene receptor 1 (CysLT1) may promote dopamine beta hydroxylase injury (Ding et al., 2007) and that increased 5-LOX expression and activity lead to production of brain-toxic molecules (Khan et al., 2010). However,

• Western blot results showed that the expressions of SOCS and

  2024-11-27

  

  Western blot results showed that the expressions of SOCS1 and SOCS3 significantly increased after administration of rGas6 24h after MCAO (Fig. 7A–C p Discussion After ischemic stroke, inflammation has been shown to be an important secondary injury mediator in patients, as well as in animals (Herz

• br Conclusion GroEL from RA

  2024-11-27

  

  Conclusion GroEL from RA-CH-1 was expressed and purified. The recombinant RaGroEL protein exhibited ATPase activity, which cooperated with GroES in ATP hydrolysis. Furthermore, the expression pattern of groEL revealed that groEL was up-regulated during stress response. Further studies are warrant

• ATM dependent initiation of radiation induced

  2024-11-27

  

  ATM-dependent initiation of radiation-induced G2/M checkpoint arrest is well established [11], [34], [35]. However, the ATR pathway may also be involved [36], [37]. Brown and Baltimore generated Cre/lox-conditional cell lines or LDN193189 with a kinase inactive allele of ATR (ATRkd) to evaluate the

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