• br Conclusions and future direction ER PgR breast

  2024-12-26

  

  Conclusions and future direction ER(−)/PgR(+) breast cancers have a distinct clinical course, response to treatment, and molecular features when compared to other breast cancer types, however some of them are actually technical artifacts or consequences of too high definitions of positivity. Acco

• br The role of apelin in hepatic diseases The involvement

  2024-12-26

  

  The role of apelin in hepatic diseases The involvement of the apelin/APJ system in liver physiology and pathology has been proven in numerous studies (Table 6). For instance, in the experiment of Emam et al. [63] on rats suffering from hepatic injury, apelin decreased the levels of ALT, AST and L

• Bamboo shoots with their high nutritive http www apexbt com

  2024-12-26

  

  Bamboo shoots, with their high nutritive and therapeutic value, are now used for food fortification (Nirmala & Bisht, 2017). Several value-added products such as nuggets, crackers, chutney, snacks, cookies, cakes, chappaties, and buns have been prepared from bamboo shoots (Table 3). Dietary fiber fr

• Plant-derived anthraquinone Overall we found maternal antibi

  2024-12-26

  

  Overall, we found maternal Plant-derived anthraquinone to be associated with improved outcomes. In these multiple logistic regression models, high postnatal empiric infant antibiotic exposure was not significantly associated with risk for NEC or LOS. However, consistent with previous studies,5, 6 r

• br Conclusions In summary we report

  2024-12-26

  

  Conclusions In summary, we report a novel preliminary finding of a potential racial difference in the association of Cd-content and AR expression in prostate cancer that will need to be confirmed in larger studies. Although the association of Cd and AR protein expression is not strong in tumor ti

• br Brain Angiotensin II receptors The

  2024-12-26

  

  Brain Angiotensin II receptors The information above leaves Angiotensin II receptors as the only RAAS components for which localization, regulation of expression and function in the N6-methyladenosine has been convincingly demonstrated, with the use of quantitative film and emulsion autoradiogra

• Dual antibiotic treatment br Perspectives and challenges Pre

  2024-12-25

  

  Perspectives and challenges Previously, the main focus of development of adenosine targets for pain was on A1Rs, due to prominent antinociception in multiple preclinical models and preliminary observations in human trials. However, delivery of agonists can be limited by other (e.g. cardiovascular

• sVRPs were more sensitive to ABT than

  2024-12-25

  

  sVRPs were more sensitive to ABT-702 than MSRs. This result agrees with previous reports that the activation of A1 receptors more potently inhibits sVRPs than MSRs (Nakamura et al., 1997, Otsuguro et al., 2009). Importantly, sVRPs are thought to reflex C-fiber-evoked nociceptive transmission. Nocice

• Patients with AAG often respond

  2024-12-25

  

  Patients with AAG often respond to intravenous immunoglobulin or plasma exchange. If these therapies are inadequate, ongoing immune suppression with steroids, azathioprine, mycophenylate or rituximab have been shown to be effective in case reports. Our patient seemed initially resistant to steroid t

• br Conflict of interest br Acknowledgments This work was

  2024-12-25

  

  Conflict of interest Acknowledgments This work was supported by research grant [PR26/20326] from Santander Bank/UCM. The authors would like to thank Miguel Capo, Professor of Toxicology from the Universidad Complutense de Madrid, for his counseling during the preparation of the present work.

• A variety of quinazoline or fused pyrimidine substituted

  2024-12-25

  

  A variety of quinazoline or fused pyrimidine-substituted diaminotriazoles showed sub-100nM inhibition of Axl (). Diaminotriazoles similarly substituted with quinolines, isoquinolines and benzothiazoles also showed potent Axl activity (data not shown), but generally exhibited potent cytotoxicity and

• br Results br Discussion Our finding that

  2024-12-25

  

  Results Discussion Our finding that AXL overexpression is significantly associated with poor survival in patients with high-grade serous OC is consistent with previous reports indicating that AXL regulates tumor growth in some cancers, as well as reports showing that AXL activity is involved i

• Although CP has been an important research subject

  2024-12-25

  

  Although CP has been an important research subject in the field of antigen processing and presentation, the mechanisms of presentation of intracellular astaxanthin and lycopene on black skin by MHC II received considerably less attention. Interestingly, pioneering work by the Münz laboratory has po

• Sanguinarine chloride If the lack of specificity and

  2024-12-25

  

  If the lack of specificity and the high pleiotropy may represent a problem in view of the potential chemotherapeutic features of autophagy-inducing agents, it Sanguinarine chloride may switch into an advantage in the case of chemopreventive strategies. In fact, as non-pharmacologic interventions su

• Fungal metabolite inhibitor Introduction The first use of th

  2024-12-25

  

  Introduction The first use of the term “autophagy” by a French physiologist, M. Anselmier, in a short article describing the effects of fasting in mice published in 1859, took place almost a century before Christian De Duve described it from a mechanistic point of view in a symposium on lysosomes i

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