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GS1101 br Author contributions br Conflict
2024-02-20

Author contributions Conflict of interest Acknowledgements This work was supported by the National Natural Science Foundation of China (81502276), Major Projects of Science and Technology of Health and Family Planning Commission of Hunan Province (A2017013), the Natural Science Foundation o
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Mistletoe is universal name for various
2024-02-20

Mistletoe is universal name for various species of parasitic plant which grows attached to and within the branches of host trees such as apple, elm, oak and pine. Mistletoe extract prepared from Viscum album, a species of mistletoe in the family Santalaceae, is generally known as European mistletoe
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Recent studies showed that the
2024-02-20

Recent studies showed that the increased expression of Aurora B kinase directly proportional to the tumor invasion and metastasis [61]. The Aurora B kinase regulates the PI2K/Akt signaling pathway has a significant role in tumor invasion and metastasis that leads to phosphorylation of GSK3β on ser 9
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br Regulation of V ATPase assembly in
2024-02-20

Regulation of V-ATPase assembly in response to changes in amino Genomic DNA Isolation Kit levels A central regulator of cell growth and metabolism is mTORC1 [38]. mTORC1 integrates signals from nutrient availability and growth factor receptors to control such processes as protein and lipid synth
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br Experimental section br Competing interests br Author s c
2024-02-20

Experimental section Competing interests Author's contributions Acknowledgement This research is partially supported by a seed fund for the Center for Drug Discovery and Translational Research (LS) and a research grant by Fujifilm (VPS and LS). The Sponsors played no roles in study desig
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Recent studies have demonstrated significant cross talk betw
2024-02-20

Recent studies have demonstrated significant cross-talk between XRCC1 (a key player in Mouse iPSC Chemical Reprogramming Cocktails Kit plus excision repair (BER) and single strand break repair) and DDR [30], [31], [32]. ATM and DNA-PKcs are known to be involved in the phosphorylation of XRCC1 to pr
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br Conflict of interest br Acknowledgements br Introduction
2024-02-20

Conflict of interest Acknowledgements Introduction The mitogen-activated protein kinase (MAPK) pathway is an important intracellular signaling system that regulates diverse cellular functions, such as proliferation, differentiation, and apoptosis [1]. Apoptosis signal-regulating kinase 1 (A
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Previously we have detected the expression of APJ receptor
2024-02-20

Previously, we have detected the expression of APJ receptor on stomach projecting hydroxychloroquine sulfate in DMV, in addition, icv administration of apelin-13 induced a remarkable c-Fos activation in those cells which were previously marked by a retrograde neuronal tracer fast blue (Birsen et al.
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Atherosclerosis is a chronic lipid metabolism disorder linke
2024-02-20

Atherosclerosis is a chronic lipid metabolism disorder linked with lipid accumulation within the arterial wall and subsequent formation of foam cells and vascular disease [96], [97]. The level of apelin is decreased in human atherosclerotic coronary arteries [4], and coronary collateral formation in
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In humans the superior safety
2024-02-20

In humans, the superior safety profile of lipid-associated formulations is characterized by decreased acute infusion-related reactions and dose-related nephrotoxicity, allowing the administration of larger doses and therefore similar efficacy with fewer administrations. In vitro studies and human cl
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and LO are members of the lipoxygenase
2024-02-19

5- and 12/15-LO are members of the lipoxygenase family that convert arachidonic Canrenone into lipid mediators such as leukotriene B4 (LTB) and 12()-hydroxyeicosatetraenoic acid (HETE) and 15()-HETE, respectively. Evidence from several in vitro and in vivo studies has shown that activation of the 5
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A disfun o cognitiva p s operat ria
2024-02-19

A disfunção cognitiva pós‐operatória é uma síndrome perioperatória bem reconhecida, consequência da anestesia e cirurgia cuja causa exata permanece por esclarecer. De que forma Phloretin disfunção cognitiva pós‐operatória e a doença de Alzheimer podem estar ligadas permanece uma questão em estudo. A
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br Introduction Several studies have found that hypothalamic
2024-02-19

Introduction Several studies have found that hypothalamic Akt-mediated signaling pathways play critical roles in the regulation of food intake and mi2 metabolism in mammals [[1], [2], [3], [4], [5], [6]]. Central injections of the inhibitor of phosphoinositide 3- kinases (PI3 K, an upstream regul
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br Rapid nongenomic effects of
2024-02-19

Rapid nongenomic effects of corticosterone in an amphibian model Studies in the model organism, the roughskin newt, Taricha granulosa, over 30 years ago led to the discovery that stress can rapidly (within minutes) suppress sexual behavior (amplectic clasping) of male T. granulosa, an effect that
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In brief serotonin can interact with classes of receptors
2024-02-19

In brief, serotonin can interact with 7 classes of receptors are differentiated into 14 subtypes (Barnes and Sharp, 1999). Specifically, 5-HT1A and 5-HT2C receptors have been the most widely studied in the modulation of anxiety responses (Deakin et al., 1992; Millan, 2003). However, the studies that
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