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Climate change will have far reaching effects on how we
2019-05-18
Climate change will have far-reaching effects on how we build, organise, and manage health systems as complex institutions. Yet, to date, these challenges have largely been ignored by the research community. Despite substantial work by WHO on the interface between climate and health, two major confe
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br En Argentina la pobreza
2019-05-18
En Argentina, la pobreza como categoría organizadora de la intervención estatal triunfó en la década de los ochenta. Hacia 1984 se publicó un informe sobre La pobreza en Argentina ci-1033 la vez que su medición comenzó a constituir un asunto de Estado y un diagnóstico prevaleciente articuló de mod
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br Case A year old Caucasian male with
2019-05-17
Case 4 A 59 year old Caucasian male with a history of chronic renal insufficiency was transferred to our intensive care unit from an outside hospital, intubated secondary to respiratory failure and severe mucositis. He arrived on multiple broad spectrum thyroid hormone receptor for treatment of
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br The influx of refugees has placed tremendous strains on
2019-05-17
The influx of refugees has placed tremendous strains on existing health-care facilities in Syria neighbouring countries like Jordan. Jordan\'s apomorphine has swelled by 20% since the inception of the Syrian civil war. The response from the WHO has been splintered and timid, even in comparison wi
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SQTS is relatively rare but should
2019-05-17
SQTS is relatively rare, but should be considered if the QT interval is markedly abbreviated and the ST segment is nearly absent with peaked and symmetrical T waves. Thus far, mutations in 5 different genes have been found, but genetic testing remains investigational because these genes account for
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Our research in this area
2019-05-17
Our research in this area has been focused on understanding the highly vascular nature of RCC, which has been largely attributed to loss of function of the von Hippel-Lindau (VHL) gene and resultant vascular endothelial growth factor (VEGF) over-expression, as it is an early event during tumorgenesi
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Case reports br Discussion RV perforation is a
2019-05-17
Case reports Discussion RV perforation is a rare but serious complication of PPM and ICD implantation. It is diagnosed when at least the tip of a passive fixation lead or the screw of an active fixation lead passes through the myocardium and extends into the pericardial cavity [1]. This complica
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The investigators suggest use of doxycycline which is effect
2019-05-17
The investigators suggest use of doxycycline, which is effective for both diseases, as a possible empirical treatment at the primary level of care. Because the consequences of an untreated true case of rickettsiosis or leptospirosis are much greater than are those of unnecessary treatment, Mayxay an
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br Discussion A familial platelet
2019-05-16
Discussion A familial platelet disorder with a propensity to myeloid malignancy (FPD/MM) was first reported in 1978 and since then approximately 30 pedigrees with RUNX1 germline mutations have been reported in the literature [9,11]. The RUNX1 gene is composed of 10 exons (1–6, 7A, 7B, 7C and 8).
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br Disclosures and funding sources br Conflicts of interest
2019-05-16
Disclosures and funding sources Conflicts of interest Introduction In 1994, Leenhardt et al. first described electrocardiogram (ECG) findings of torsades de pointes and QT prolongation in patients without demonstrable structural TAE226 manufacturer disease, with the torsades de pointes ini
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In a recent study Nademanee et al
2019-05-16
In a recent study, Nademanee et al. [76]. reported additional evidence pointing to pathologic changes in the RVOT of patients with BrS that have proved undetectable by echocardiography or MRI. In contrast, imaging techniques in ARVC clearly display morphologic and functional changes (e.g., dilation
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ci-1033 At least genes are associated with familial
2019-05-16
At least 15 genes are associated with familial LQTS, with 3 of these genes accounting for 70–75% of cases [5]. Despite advances in the understanding of the molecular basis of LQTS, challenges remain in making the clinical diagnosis. Importantly, between 10–40% of gene carriers have normal QT interva
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This study provides an innovative model to harness
2019-05-16
This study provides an innovative model to harness national household survey data to quantify the effects of the various malaria control interventions. The model accounts for the spatial dependence in parasitaemia as a consequence of the heterogeneous distribution of malaria transmission and its dri
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br As the global burden of disease shifts
2019-05-16
As the global burden of disease shifts from infectious diseases to non-communicable diseases (NCDs), cancer has increasingly become a major contributor to morbidity and mortality in low-income and middle-income countries (LMICs). Major reasons for these nitric oxide synthase inhibitors shifts inc
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br Case report A year old man
2019-05-16
Case report A 63-year-old man with a history of longstanding atrial fibrillation (AF) was admitted to our hospital with anterior acute myocardial infarction (AMI). Emergency cardiac catheterization revealed chronic total occlusion of the distal right coronary artery, total occlusion of the proxim
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